SelenoDB
Release 2.0
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Gene Report for SPG00000014_2.0
Identity
GeneSECIS binding protein 2 (SBP2)
SpeciesHomo sapiens (Human)
DescriptionSBP2 encodes a nuclear protein that functions as a SECIS binding protein. Mutations in this gene have been associated with a reduction in activity of a specific thyroxine deiodinase, a selenocysteine-containing enzyme, and abnormal thyroid hormone metabolism. (NCBI)
FamilySECIS binding protein 2
Synonyms SECIS binding protein 2 (SECISBP2)
SubfamilyNone
SynonymsNone
Gene IDSPG00000014
Gene release2.0
External ID ENSG00000187742.10 (Ensembl)
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A) [Report annotation error]
Curated external database annotation (GENCODE, 15) [Report annotation error]
Conceptual translation (Translate, Standard code with Sec) [Report annotation error]
OrientationForward
Structure gene structure

FeatureCol PromoterCol Coding exonCol Non coding exon (UTR)Col IntronCol SECIS
ResidueCol SecCol Cys or Other

Gene
Transcript(s) Promoter(s) Protein(s) Secis
SPT00000050_2.0SPR00000064_2.0SPP00000054_2.0N/A
SPT00000051_2.0SPR00000065_2.0SPP00000055_2.0N/A
Genetic
Differentiation
FST
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.381
Middle East0.7210.667
Europe0.5480.5200.402
Central-South Asia0.6380.6190.4630.514
East Asia0.4840.4870.4410.3940.376
Oceania0.5120.4910.4750.4430.4370.353
America0.5260.5540.5130.4730.4650.5210.464

High FST

Low FST

P-value
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.193
Middle East0.0090.083
Europe0.0360.0060.031
Central-South Asia0.0000.0000.0010.001
East Asia0.0000.0000.0000.0000.000
Oceania0.0170.0170.0090.0050.0600.333
America0.0000.0000.0000.0000.0000.0640.054

Low P-value

High P-value

Sequence
Sequence SEQ00000014_2.0
External ID ENSG00000187742.10 (Ensembl)
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