SelenoDB
Release 2.0
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Gene Report for SPG00000039_2.0
Identity
GeneThioredoxin reductase 3 (TR3)
SpeciesHomo sapiens (Human)
DescriptionThis gene encodes a member of the family of pyridine nucleotide oxidoreductases. This protein catalyzes the reduction of thioredoxin, and is implicated in the defense against oxidative stress. (NCBI)
FamilyThioredoxin reductase
Synonyms Thioredoxin reductase (TrxR)
Subfamily Thioredoxin reductase 3 (TR3)
Synonyms Thioredoxin reductase 2 (TR2)
Thioredoxin reductase 3 (TrxR3)
Gene IDSPG00000039
Gene release2.0
External ID ENSG00000197763.8 (Ensembl)
Annotation
Prediction method(s)
Promoter prediction (5000bp upstream, N/A) [Report annotation error]
Curated external database annotation (GENCODE, 15) [Report annotation error]
Thermodynamic pattern-based SECIS prediction (SECISearch, 3.0) [Report annotation error]
Conceptual translation (Translate, Standard code with Sec) [Report annotation error]
OrientationReverse
Structure gene structure

FeatureCol PromoterCol Coding exonCol Non coding exon (UTR)Col IntronCol SECIS
ResidueCol SecCol Cys or Other

Gene
Transcript(s) Promoter(s) Protein(s) Secis
SPT00000133_2.0SPR00000172_2.0SPP00000141_2.0SPS00000049_2.0
SPT00000134_2.0SPR00000173_2.0SPP00000142_2.0SPS00000050_2.0
SPT00000135_2.0SPR00000174_2.0SPP00000143_2.0SPS00000051_2.0
Genetic
Differentiation
FST
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.285
Middle East0.6700.536
Europe0.5800.4770.540
Central-South Asia0.5180.4680.4690.364
East Asia0.3360.3180.3840.2680.260
Oceania0.4420.5140.5130.4620.3560.393
America0.3440.3430.3760.3280.3190.2610.429

High FST

Low FST

P-value
AfricaMiddle EastEuropeCentral-South AsiaEast AsiaOceaniaAmerica
Africa0.712
Middle East0.0830.326
Europe0.0010.0170.000
Central-South Asia0.1550.1660.0000.068
East Asia0.2790.0020.0000.0000.000
Oceania0.1630.0090.0050.0020.3570.312
America0.3810.0090.0010.0010.0000.6070.054

Low P-value

High P-value

Sequence
Sequence SEQ00000039_2.0
External ID ENSG00000197763.8 (Ensembl)
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